Investigation Of Levels Of Luteinizing Hormone And Follicular Stimulating Hormone Among Women With Polycystic Ovary Syndrome In Abakaliki, Nigeria

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P-228: Altered Expression of Folliclestimulating Hormone Receptor and Luteinizing Hormone Receptor in Granulosa Cells from Women with Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is a common complex genetic endocrinopathy, affecting 5 - 10% of women at reproductive age. PCO granulosa cells seem to have abnormal responses to follicle- stimulating hormone (FSH). FSH is considered to be a pituitary glycoprotein that plays an important role during folliculogenesis as it promotes the proliferation and differentiation of granulosa ...

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Association of the genetic variants of luteinizing hormone, luteinizing hormone receptor and polycystic ovary syndrome

BACKGROUND High circulating luteinizing hormone (LH) level is a typical biochemical feature of polycystic ovary syndrome (PCOS) whose pathophysiology is still unclear. Certain mutations of LH and LH receptor (LHR) may lead to changes in bioactivity of these hormones. The aim of this study was determine the role of the LH and LHR polymorphisms in the pathogenesis of PCOS using a genetic approach...

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ژورنال

عنوان ژورنال: IOSR Journal of Nursing and Health Science

سال: 2016

ISSN: 2320-1940,2320-1959

DOI: 10.9790/1959-050403104107